After not running Monday and Tuesday due to trans-Atlantic travel, I just ran tonight after the holiday. I got in a 9.3km run, and my body felt tired.
I would guess the tired was due to a combination of factors, including trans-atlantic travel, back to Bet Shemesh hilliness after a week and a half of running flat Chicago, and a crazy messed up schedule over shavuos holiday with the up all night learning programs.
Anyways, I am happy I got out for the run and am looking forward to another tired run tomorrow. Maybe Friday will be back to normal.